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Registration
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Abstracts
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Travel Award
All SBI students and pos-doc are eligible for financial support See rUles here
Scientific Program
September, 29
September, 30
October, 01
October, 02
Açores Room | |||
14:00 - 18:00 | Registration | ||
18:00 - 18:30 | Opening Ceremony | ||
18:30 - 19:00 | SBI Women in Science Award | ||
19:00 - 20:00 | Opening Conference Chair: Claudia Brodskyn Lieping Chen Tumor microenvironment as a target of immunotherapy |
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20:00 - 22:00 | Cocktail |
Pico Room | Ilha Room | São Miguel Room | Flores Room | |
7:30 - 8:30 | BD Biosciences course in Immunotherapy Iris Castro High dimension cell-Analysis in immunotherapy: FlowJo Supporting your Discoveries |
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8:30 - 9:00 | Break | Break | Break | Break |
9:00 - 11:00 | Symposium in Immunotherapeutical intervention on leukocyte trafficking Chair: Loic Dupré | Symposium in Metabolic regulation in immune cells Chair: José Alves Filho | Extra Section of Clinical Immunology (ESCI) Joint Symposium with the Brazilian Society of Clinical Oncology (SBOC) in Cancer immunotherapy Chair: Carlos Gil Ferreira | Symposium The multiple dimensions of immunology: A tribute to George Alexandre dos Reis Chair: Marcello Barcinski |
9:00 - 9:30 | Emmanuel Donnadieu Imaging CAR-T cell migration in tumors | Kelly Magalhães Adipose organ plasticity and cancer modulation | Eliane Piaggio Immune landscape of rhabdoid tumors: Non- genetic mechanisms of tumor immunogenicity | Adriana Bonomo From self-recognition to cancer immunobiology |
9:30 - 10:00 | Lisa Westerberg Targeting actin regulators in cancer therapy | Luciana Berod Metabolic regulation of Treg cells | Ricardo Weinlich RIPK3 is an overall survival predictor and is associated with altered immunemodulation in lower grade glioma patients | Maria Bellio The CD4 T cell response during infection by Trypanosoma cruzi |
10:00 - 10:30 | Gustavo Menezes Your liver may be sick, and you do not know: imaging the immune system during asymptomatic steatosis | Niels Olsen Saraiva Camara Sirtuin 1 and cell metabolism in innate and adaptive cells | Andreia Melo Evolving paradigms in melanoma therapy | Marcela Lopes Efferocytosis by TAM receptors in macrophage-mediated immunity to Trypanosoma cruzi |
10:30 - 11:00 | Jens Stein CD8+ T cell immune surveillance of non-lymphoid tissue | Jeff Rathmell Fueling T cells in inflammation and cancer | Kenneth Gollob Immunoregulatory mechanisms associated with failure of checkpoint inhibitor immunotherapy in cancer | Alessandra Filardy Efferocytosis mediated by TAM receptors modulates lung mucosae homeostasis |
11:00 - 11:30 | Coffee Break | Coffee Break | Coffee Break | |
11:30 - 12:30 | Morning conference Chair: Vinicius Cotta de Almeida | Morning conference Chair: Patricia Bozza | Extra Section of Clinical Immunology (ESCI) Morning conference Chair: Cristina Bonorino |
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Minsoo Kim Initiation and resolution of neutrophil response during infection | Tim Sparwasser Metabolic checkpoints controlling immune cell function | Enfu Hui How anti-PD-1 differs from anti-PD-L1: A cell biology perspective |
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12:30 - 15:30 | Lunch | Lunch | Lunch | |
12:30 - 14:00 | Backman-Coulter symposium Olindo Assis Martins Filho and Andréa Teixeira de Carvalho Instituto René Rachou, Fiocruz Characterization of circulating microvesicles in sepsis and infectious endocarditis patients | BD Biosciences symposium Robert Balderas VP for Biological Sciences High-dimensional analysis of single cells: The path to 50 parameter and beyond | José de Moura Leite Netto Brazilian Network of Journalists and Science Communicators The power of science popularization |
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14:00 - 15:30 | Break | Break | Break | |
15:30 - 17:00 | Express presentation in Innate immunity Chair: Flavia Carneiro | Express presentation in Signaling and molecular immunology Chair: Eugenio Hottz | Express presentation in Inflammation and immunopharmacology Chair: Josiane Neves |
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15:30 - 15:52 | Flavia Carneiro An essential role for ECSIT in mitochondrial complex I assembly and mitophagy in macrophages | Eugenio Hottz Beyond LPS sensing: TLR-4-induced platelet activation by DENV NS1 and circulating extracellular histones in dengue | Josiane Neves Inflammation and extracellular DNA traps: Untangling a tangle-web |
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15:52 - 16:09 | Camila Meirelles de Souza Silva Caspase 11/Gasdermin D-dependent netosis plays a vital role in the inflammation and organ damage during sepsis | Axel Fogaça Rosado NLRP3 inflammasome inhibition counteracts behavioural, neurochemical and neuroinflammatory modifications induced by chronic stress in female mice | Julia Góes Porfirio Evaluation of the role of 12(S)-Hete in vascular leakage in Dengue fever |
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16:09 - 16:26 | Barbara Simonson Gonçalves Neutrophil extracellular traps from healthy donors and from HIV-1-infected patients restrain HIV-1 infection in macrophages | Bárbara Costa Peixoto Role of the transcriptional co-factor IRF2BP2 in Th1 cell polarization and IFN-γ expression | Vívian Louise Soares de Oliveira FcγRIIγ And FcγRIII have opposite functions in controlling bacterial clearance and joint inflammation in Staphylococcus Aureus-induced arthritis |
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16:26 - 16:43 | Anna Julia Pietrobon Inhibition of HIV-I replication in neonatal macrophages by IFN-I adjuvants | Carlos Arterio Sorgi Tumour microenvironment metabolites induced modulation of macrophage activity and reprogram lipid metabolism | Gabriel Azevedo Publio Metabolic reprogramming plays a critical role in IL-17α driven keratinocyte activation in psoriasis through NFkB-pathway mechanism |
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16:43 - 17:00 | Ana Carolina Guerta Salina Skin resident macrophage-derived microRNA21 drives susceptibility to Staphylococcus aureus infection | Guilherme Afonso Melo The epigenetic modulator Prc1 in CD8 T cell differentiation | Lohanna Palhinha do Amaral Leptin induces proinflammatory and pro-adipogenic signalling in adipocytes |
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17:00 - 18:00 | Twilight conference Chair: Gustavo Amarante-Mendes | Twilight conference Chair: Lucas Carvalho | Extra Section of Clinical Immunology (ESCI) Twilight conference Chair: Ana Paula Lepique |
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Mark Ansel Molecular regulation of tissue immunity | Mauro Teixeira Immunotherapy with drugs that induce the resolution of inflammation | Luisa Villa Pathways to the elimination of HPV-induced cancer |
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18:00 - 18:30 | Coffee Break | Coffee Break | Coffee Break |
Açores Room | ||||
18:30 - 19:30 | Keynote conference Chair: Helder Nakaya |
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Rafi Ahmed T cell exhaustion and PD-1 immunotherapy |
Cascaes Room | ||||
19:30 - 22:00 | POSTER SESSION WITH HAPPY HOUR |
Pico Room | Ilha Room | São Miguel Room | Flores Room | |
7:30 - 8:30 | BD Biosciences course in Immunotherapy Flavia Calmon High dimension cell-Analysis in immunotherapy: Experiment design matters |
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8:30 - 9:00 | Break | Break | Break | |
9:00 - 11:00 | Symposium in T cell activation and exhaustion Chair: André Vale | Symposium in Immunoregulation Chair: Marcelo Bozza | Extra Section of Clinical Immunology (ESCI) Joint Symposium with the Brazilian Society of Rheumatology (SBR) in Autoimmune diseases Chair: Eduardo Paiva |
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9:00 - 9:30 | Renata Meireles Control of CD8 T cell differentiation by polycomb group proteins | Claudia Benjamim Can a protein cannabinoid be a future treatment for sepsis and its late consequences | Luis Eduardo Coelho Andrade Pre-autoimmunity: A unique opportunity for understanding and modulating autoimmune diseases |
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9:30 - 10:00 | Alice Kamphorst Costimulation and CD8 T cell exhaustion | Ana Paula Lepique Interplay between STAT3 and p6 NFkappaB modulates T cell anti-tumor immune responses | Paulo Louzada Júnior Innate immune response as a therapeutic target in autoimmune diseases |
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10:00 - 10:30 | Ben Youngblood T-cell intrinsic and extrinsic mechanisms limiting tumor immunotherapy | Daniel Mansur ISG15 is a circumstantial antiviral protein | Denise Fonseca Acute mucosal infection imposes a long-term remodeling of host metabolism in a microbiota-dependent manner |
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10:30 - 11:00 | Peter Sage Regulation of B cell responses by follicular T cells | Bernardo Franklin Platelets fuel the inflammasome activation of innate immune cells | Mary Keir The immune response in inflammatory bowel disease |
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11:00 - 11:30 | Coffee Break | Coffee Break | Coffee Break | |
11:30 - 12:30 | Morning conference Chair: Moises Bauer | Morning conference Chair: Julio Scharfstein | Extra Section of Clinical Immunology (ESCI) Morning conference Chair: Ana Caetano de Farias |
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Graham Pawelec Ageing and the human immune system | Francesca Granucci Ca2+ regulated pathways downstream of pattern recognition receptors | Scott Snapper Cytokines, cytokine signaling and inflammatory bowel disease: Novel mechanisms and therapeutic implications through the study of rare diseases |
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12:30 - 15:30 | Lunch | Lunch | Lunch | |
12:30 - 14:00 | Satellite symposium | SBI-BD Biosciences investigator award Finalist oral presentation | José de Moura Leite Netto Brazilian Network of Journalists and Science Communicators The power of science popularization |
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14:00 - 15:30 | Break | Break | SBI Thereza Kipnis Award (14:00-16:30) Chair: Lis Antonelli |
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15:30 - 17:00 | Express presentation in Immunity to infection and host defense Chair: Pritesh Lalwani | Express presentation in Cellular and mucosal immunology Chair: Bernado Reis |
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15:30 - 15:52 | Pritesh Lalwani IDO-AHR axis: Vivax malaria | Bernado Reis The role of intraepithelial lymphocytes in colon cancer | 14:00 - 14:30 Camila R.R. Barbosa New malaria vaccine candidates: identification and validation of peptides presented by HLA-I in reticulocytes infected with Plasmodium vivax using immunopeptidomics |
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15:52 - 16:09 | Cecilia Bataglioli Cavazzoni B cell subsets and immunoglobulin repertoire dynamics during Zika virus experimental infection | Rafaela Mano Guimarães Blood-circulating leukocytes fail to infiltrate the spinal cord and dorsal root ganglia parenchyma after spared nerve injury | 14:30 - 15:00 Luis Eduardo A. Damasceno The glycolytic enzyme PKM2 promotes Th17 cell development and mediated autoimmune inflammation |
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16:09 - 16:26 | Beatriz Macedo de Oliveira Rocha Associations between obesity and gut microbiota during experimental tuberculosis: impact on lipid metabolism | Anna Cecíllia Quirino Teixeira Dengue virus non-structural protein 1 activates platelets and induces secretion of proinflammatory mediators partially through TLR4 | 15:00 - 15:30 Brenda Naemi Nakagaki Immune and metabolic shifts during neonatal development reprogram liver identity and function |
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16:26 - 16:43 | Julia da Cunha Santos Mechanisms of lipid droplets biogenesis in macrophages infected by Escherichia Coli | Fernando Bandeira Sulczwski STAT6 Signaling pathway modulates follicular helper T cell fate and germinal center formation in immune responses promoted by type 2 conventional dendritic cells | 15:30 - 16:00 Gretel R. Rodríguez Control of STAT-3 and NF-kB signaling by IL-6 and G-CSF in local and systemic immune response in HPV tumor bearing hosts |
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16:43 - 17:00 | Luísa Menezes Silva Omentum as a new component of the mucosal firewall | Maria Tereza Martinez The influence of ketogenic diet in gut immune homeostasis | 16:00 - 16:30 Maria Claudia da Silva Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis |
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17:00 - 18:00 | Twilight conference Chair: Roque Pacheco | Twilight conference Chair: Dario Zamboni | Twilight conference Chair: Camila Indiani |
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Edgar de Carvalho Use of topical imunomodulators in the therapy of cutaneous Leishmaniasis | Fernando Cunha Do neutrophil extracellular traps (NETs) play a relevant role in the pathology of inflammatory diseases? | Walderez Dutra Using immunoregulatory networks to instruct therapeutic interventions in human parasitic diseases |
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18:00 - 18:30 | Coffee Break | Coffee Break | Coffee Break |
Açores Room | ||||
18:30 - 19:30 | KEYNOTE CONFERENCE CHAIR: RODRIGO CORREA |
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FIONA POWRIE GUT REACTIONS: IMMUNE PATHWAYS IN THE INTESTINE IN HEALTH AND DISEASE |
Cascaes Room | ||||
19:30 - 22:00 | Poster Session with Happy Hour |
Pico Room | Ilha Room | São Miguel Room | Flores Room | |
7:30 - 8:30 | BD Biosciences course in Immunotherapy Lucas Rizzo High dimension cell-Analysis in immunotherapy: Expanding cell boundaries by integrating sorting and transcriptome |
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8:30 - 9:00 | Break | Break | Break | |
9:00 - 11:00 | Joint Symposium with the Society for Leukocyte Biology (SLB) in Target leukocyte for immunotherapy Chair: Martin Bonamino | Symposium in Vaccines Chair: Helder Nakaya | Extra Section of Clinical Immunology (ESCI) Joint Symposium with the Brazilian Association of Allergy and Immunology (ASBAI) in Allergic diseases Chair: Edecio Cunha-Neto |
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9:00 - 9:30 | Miriam Werneck In vitro differentiated memory cells as a tool for immunotherapy | Ricardo Palacios Dengue vaccine immune response: Between wishful thinking and good enough | João Negreiros Tebyriçá Allergy Immunotherapy: Immunological mechanisms and clinical indications |
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9:30 - 10:00 | Marco Davila Mutation of the CD28 endodomain confers resistance of CAR-T cells to exhaustion | Olindo Martins Filho Impact of synthetic and biological immunotherapy on the duration of immunity induced by the 17DD yellow fever vaccine | Pedro Giavina Bianchi Immunomodulation of type 2 inflammation with monoclonal antibodies |
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10:00 - 10:30 | Sven Brandau Tumor-associated neutrophils: Mediators of tumor progression and targets for combination immunotherapy | Esper Kallas Development of vaccines to prevent Zika | Momtchilo Russo Specific immunotherapy associated with TLR9 agonist for experimental asthma |
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10:30 - 11:00 | Jose Conejo-Garcia Coordinated T and B cell responses spontaneously protect against ovarian cancer progression | Daniela Ferreira Experimental human pneumococcal challenge for vaccine development | Caroline Sokol Innate control of allergic immunity: New players, new pathways |
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11:00 - 11:30 | Coffee Break | Coffee Break | Coffee Break | |
11:30 - 12:30 | Morning conference Chair: João Trindade Marques | Morning conference Chair: Karina Bortoluci | Extra Section of Clinical Immunology (ESCI) Morning conference Chair: Lis Antonelli |
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Rosa Bacchetta Lentiviral-mediated gene transfer to convert T cells into Treg cells: New generation immune therapies | Ricardo Gazzinelli The circadian cycle and malaria: The sweet side of the story | Irini Sereti Idiopathic CD4 lymphopenia: A new kid on the autoimmunity block? |
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12:30 - 15:30 | Lunch | Lunch | Lunch | |
12:30 - 14:00 | SBI general assembly (13:30-15:00) | Satellite symposium | Satellite symposium | |
14:00 - 15:30 | Break | Break | Break | |
15:30 - 17:00 | Express presentation in Tumor and clinical immunology Chair: Rodrigo Ramos | Express presentation in Immuneregulation in diseases Chair: Larissa Cunha | Express presentation in Immunotherapy and vaccine Chair: Eduardo Lani Silveira |
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15:30 - 15:52 | Rodrigo Ramos Unrevealing tumor-associated macrophages heterogeneity in breast cancer patients | Larissa Cunha The role of autophagy in the functional polarization of tumor-associated macrophages | Eduardo Lani Silveira Tryptophan metabolism drives the Dengue virus-mediated B cell differentiation into antibody-secreting cells |
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15:52 - 16:09 | Murillo Duarte Silva The use of biologicals in top-down approach: a more promising strategy to induce remission and inflammation control in Crohn’s disease patients under anti-TNF therapy | Camila Figueiredo Pinzan Melatonin treatment restores the balance between activated and regulatory responses in intestinal immunity during experimental Toxoplasma Gondii infection | Alexandre de Magalhães Vieira Machado Assessment of the protective efficacy of a vaccine based on a recombinant influenza virus against S. Pneumoniae |
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16:09 - 16:26 | Glauco Akelinghton Freire Vitiello Identification of MMTV-env sequences in Brazilian breast cancer patients and in silico predicted epitopes from MMTV Env protein as potential immunogenic targets | Cristhiane Favero de Aguiar Tissue-specific regulation of NKT cell metabolism drives their function and contributes to obesity | Isaú Henrique Noronha Intranasal vaccine against Trypanosoma cruzi mediates antibody protective responsi |
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16:26 - 16:43 | Luciana Rodrigues Carvalho Barros Three-compartment mathematical model CAR-T cell immunotherapy | Renato da Silva Cardoso Relationship between cholinergic anti-inflammatory pathway and wound healing process: a perfect match? | Victória Alves Santos Lunardelli Immunization with different ZIKV envelope proteins induces long-term humoral and cellular immunity in mice |
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16:43 - 17:00 | Nayara Gusmão Tessarollo Down-regulation of neoantigens promoted by treatment of B16F10 cells with P19ARF and IFN- | Wesley Nogueira Brandão NMDA ionotropic receptor signalling on the ontogeny of T-lymphocytes and its repercussion in the development of experimental autoimmune encephalomyelitis | João Pedro da Silva Nunes Assessment of the immunogenicity of the leptospiral Lipl32, ligani, and ligbrep recombinant proteins in the sheep model |
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17:00 - 17:30 | Coffee Break | Coffee Break | Coffee Break |
Açores Room | ||||
17:30 - 18:30 | CLOSING CONFERENCE CHAIR: Ricardo Gazzinelli |
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JORGE KALIL FUTURE OF VACCINES: THE FIRST IMMUNOMODULATOR |
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18:30 - 19:00 | Awards announcement and Closing remarks |
Cascaes Room | ||||
21:00 | Farewell party |
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