Scientific Program

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Registration

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Travel Award

All SBI students and pos-doc are eligible for financial support See rUles here

September, 29

September, 30

October, 01

October, 02

	Açores Room
14:00 - 18:00	Registration
18:00 - 18:30	Opening Ceremony
18:30 - 19:00	SBI Women in Science Award
19:00 - 20:00	Opening Conference Chair: Claudia Brodskyn Lieping Chen Tumor microenvironment as a target of immunotherapy
20:00 - 22:00	Cocktail

	Pico Room	Ilha Room	São Miguel Room	Flores Room
7:30 - 8:30				BD Biosciences course in Immunotherapy Iris Castro High dimension cell-Analysis in immunotherapy: FlowJo Supporting your Discoveries
8:30 - 9:00	Break	Break	Break	Break
9:00 - 11:00	Symposium in Immunotherapeutical intervention on leukocyte trafficking Chair: Loic Dupré	Symposium in Metabolic regulation in immune cells Chair: José Alves Filho	Extra Section of Clinical Immunology (ESCI) Joint Symposium with the Brazilian Society of Clinical Oncology (SBOC) in Cancer immunotherapy Chair: Carlos Gil Ferreira	Symposium The multiple dimensions of immunology: A tribute to George Alexandre dos Reis Chair: Marcello Barcinski
9:00 - 9:30	Emmanuel Donnadieu Imaging CAR-T cell migration in tumors	Kelly Magalhães Adipose organ plasticity and cancer modulation	Eliane Piaggio Immune landscape of rhabdoid tumors: Non- genetic mechanisms of tumor immunogenicity	Adriana Bonomo From self-recognition to cancer immunobiology
9:30 - 10:00	Lisa Westerberg Targeting actin regulators in cancer therapy	Luciana Berod Metabolic regulation of Treg cells	Ricardo Weinlich RIPK3 is an overall survival predictor and is associated with altered immunemodulation in lower grade glioma patients	Maria Bellio The CD4 T cell response during infection by Trypanosoma cruzi
10:00 - 10:30	Gustavo Menezes Your liver may be sick, and you do not know: imaging the immune system during asymptomatic steatosis	Niels Olsen Saraiva Camara Sirtuin 1 and cell metabolism in innate and adaptive cells	Andreia Melo Evolving paradigms in melanoma therapy	Marcela Lopes Efferocytosis by TAM receptors in macrophage-mediated immunity to Trypanosoma cruzi
10:30 - 11:00	Jens Stein CD8+ T cell immune surveillance of non-lymphoid tissue	Jeff Rathmell Fueling T cells in inflammation and cancer	Kenneth Gollob Immunoregulatory mechanisms associated with failure of checkpoint inhibitor immunotherapy in cancer	Alessandra Filardy Efferocytosis mediated by TAM receptors modulates lung mucosae homeostasis
11:00 - 11:30	Coffee Break	Coffee Break	Coffee Break
11:30 - 12:30	Morning conference Chair: Vinicius Cotta de Almeida	Morning conference Chair: Patricia Bozza	Extra Section of Clinical Immunology (ESCI) Morning conference Chair: Cristina Bonorino
11:30 - 12:30	Minsoo Kim Initiation and resolution of neutrophil response during infection	Tim Sparwasser Metabolic checkpoints controlling immune cell function	Enfu Hui How anti-PD-1 differs from anti-PD-L1: A cell biology perspective
12:30 - 15:30	Lunch	Lunch	Lunch
12:30 - 14:00	Backman-Coulter symposium Olindo Assis Martins Filho and Andréa Teixeira de Carvalho Instituto René Rachou, Fiocruz Characterization of circulating microvesicles in sepsis and infectious endocarditis patients	BD Biosciences symposium Robert Balderas VP for Biological Sciences High-dimensional analysis of single cells: The path to 50 parameter and beyond	José de Moura Leite Netto Brazilian Network of Journalists and Science Communicators The power of science popularization
14:00 - 15:30	Break	Break	Break
15:30 - 17:00	Express presentation in Innate immunity Chair: Flavia Carneiro	Express presentation in Signaling and molecular immunology Chair: Eugenio Hottz	Express presentation in Inflammation and immunopharmacology Chair: Josiane Neves
15:30 - 15:52	Flavia Carneiro An essential role for ECSIT in mitochondrial complex I assembly and mitophagy in macrophages	Eugenio Hottz Beyond LPS sensing: TLR-4-induced platelet activation by DENV NS1 and circulating extracellular histones in dengue	Josiane Neves Inflammation and extracellular DNA traps: Untangling a tangle-web
15:52 - 16:09	Camila Meirelles de Souza Silva Caspase 11/Gasdermin D-dependent netosis plays a vital role in the inflammation and organ damage during sepsis	Axel Fogaça Rosado NLRP3 inflammasome inhibition counteracts behavioural, neurochemical and neuroinflammatory modifications induced by chronic stress in female mice	Julia Góes Porfirio Evaluation of the role of 12(S)-Hete in vascular leakage in Dengue fever
16:09 - 16:26	Barbara Simonson Gonçalves Neutrophil extracellular traps from healthy donors and from HIV-1-infected patients restrain HIV-1 infection in macrophages	Bárbara Costa Peixoto Role of the transcriptional co-factor IRF2BP2 in Th1 cell polarization and IFN-γ expression	Vívian Louise Soares de Oliveira FcγRIIγ And FcγRIII have opposite functions in controlling bacterial clearance and joint inflammation in Staphylococcus Aureus-induced arthritis
16:26 - 16:43	Anna Julia Pietrobon Inhibition of HIV-I replication in neonatal macrophages by IFN-I adjuvants	Carlos Arterio Sorgi Tumour microenvironment metabolites induced modulation of macrophage activity and reprogram lipid metabolism	Gabriel Azevedo Publio Metabolic reprogramming plays a critical role in IL-17α driven keratinocyte activation in psoriasis through NFkB-pathway mechanism
16:43 - 17:00	Ana Carolina Guerta Salina Skin resident macrophage-derived microRNA21 drives susceptibility to Staphylococcus aureus infection	Guilherme Afonso Melo The epigenetic modulator Prc1 in CD8 T cell differentiation	Lohanna Palhinha do Amaral Leptin induces proinflammatory and pro-adipogenic signalling in adipocytes
17:00 - 18:00	Twilight conference Chair: Gustavo Amarante-Mendes	Twilight conference Chair: Lucas Carvalho	Extra Section of Clinical Immunology (ESCI) Twilight conference Chair: Ana Paula Lepique
17:00 - 18:00	Mark Ansel Molecular regulation of tissue immunity	Mauro Teixeira Immunotherapy with drugs that induce the resolution of inflammation	Luisa Villa Pathways to the elimination of HPV-induced cancer
18:00 - 18:30	Coffee Break	Coffee Break	Coffee Break

		Açores Room
18:30 - 19:30	Keynote conference Chair: Helder Nakaya
	Rafi Ahmed T cell exhaustion and PD-1 immunotherapy

		Cascaes Room
19:30 - 22:00	POSTER SESSION WITH HAPPY HOUR

	Pico Room	Ilha Room	São Miguel Room	Flores Room
7:30 - 8:30				BD Biosciences course in Immunotherapy Flavia Calmon High dimension cell-Analysis in immunotherapy: Experiment design matters
8:30 - 9:00	Break	Break	Break
9:00 - 11:00	Symposium in T cell activation and exhaustion Chair: André Vale	Symposium in Immunoregulation Chair: Marcelo Bozza	Extra Section of Clinical Immunology (ESCI) Joint Symposium with the Brazilian Society of Rheumatology (SBR) in Autoimmune diseases Chair: Eduardo Paiva
9:00 - 9:30	Renata Meireles Control of CD8 T cell differentiation by polycomb group proteins	Claudia Benjamim Can a protein cannabinoid be a future treatment for sepsis and its late consequences	Luis Eduardo Coelho Andrade Pre-autoimmunity: A unique opportunity for understanding and modulating autoimmune diseases
9:30 - 10:00	Alice Kamphorst Costimulation and CD8 T cell exhaustion	Ana Paula Lepique Interplay between STAT3 and p6 NFkappaB modulates T cell anti-tumor immune responses	Paulo Louzada Júnior Innate immune response as a therapeutic target in autoimmune diseases
10:00 - 10:30	Ben Youngblood T-cell intrinsic and extrinsic mechanisms limiting tumor immunotherapy	Daniel Mansur ISG15 is a circumstantial antiviral protein	Denise Fonseca Acute mucosal infection imposes a long-term remodeling of host metabolism in a microbiota-dependent manner
10:30 - 11:00	Peter Sage Regulation of B cell responses by follicular T cells	Bernardo Franklin Platelets fuel the inflammasome activation of innate immune cells	Mary Keir The immune response in inflammatory bowel disease
11:00 - 11:30	Coffee Break	Coffee Break	Coffee Break
11:30 - 12:30	Morning conference Chair: Moises Bauer	Morning conference Chair: Julio Scharfstein	Extra Section of Clinical Immunology (ESCI) Morning conference Chair: Ana Caetano de Farias
11:30 - 12:30	Graham Pawelec Ageing and the human immune system	Francesca Granucci Ca2+ regulated pathways downstream of pattern recognition receptors	Scott Snapper Cytokines, cytokine signaling and inflammatory bowel disease: Novel mechanisms and therapeutic implications through the study of rare diseases
12:30 - 15:30	Lunch	Lunch	Lunch
12:30 - 14:00	Satellite symposium	SBI-BD Biosciences investigator award Finalist oral presentation	José de Moura Leite Netto Brazilian Network of Journalists and Science Communicators The power of science popularization
14:00 - 15:30	Break	Break	SBI Thereza Kipnis Award (14:00-16:30) Chair: Lis Antonelli
15:30 - 17:00	Express presentation in Immunity to infection and host defense Chair: Pritesh Lalwani	Express presentation in Cellular and mucosal immunology Chair: Bernado Reis
15:30 - 15:52	Pritesh Lalwani IDO-AHR axis: Vivax malaria	Bernado Reis The role of intraepithelial lymphocytes in colon cancer	14:00 - 14:30 Camila R.R. Barbosa New malaria vaccine candidates: identification and validation of peptides presented by HLA-I in reticulocytes infected with Plasmodium vivax using immunopeptidomics
15:52 - 16:09	Cecilia Bataglioli Cavazzoni B cell subsets and immunoglobulin repertoire dynamics during Zika virus experimental infection	Rafaela Mano Guimarães Blood-circulating leukocytes fail to infiltrate the spinal cord and dorsal root ganglia parenchyma after spared nerve injury	14:30 - 15:00 Luis Eduardo A. Damasceno The glycolytic enzyme PKM2 promotes Th17 cell development and mediated autoimmune inflammation
16:09 - 16:26	Beatriz Macedo de Oliveira Rocha Associations between obesity and gut microbiota during experimental tuberculosis: impact on lipid metabolism	Anna Cecíllia Quirino Teixeira Dengue virus non-structural protein 1 activates platelets and induces secretion of proinflammatory mediators partially through TLR4	15:00 - 15:30 Brenda Naemi Nakagaki Immune and metabolic shifts during neonatal development reprogram liver identity and function
16:26 - 16:43	Julia da Cunha Santos Mechanisms of lipid droplets biogenesis in macrophages infected by Escherichia Coli	Fernando Bandeira Sulczwski STAT6 Signaling pathway modulates follicular helper T cell fate and germinal center formation in immune responses promoted by type 2 conventional dendritic cells	15:30 - 16:00 Gretel R. Rodríguez Control of STAT-3 and NF-kB signaling by IL-6 and G-CSF in local and systemic immune response in HPV tumor bearing hosts
16:43 - 17:00	Luísa Menezes Silva Omentum as a new component of the mucosal firewall	Maria Tereza Martinez The influence of ketogenic diet in gut immune homeostasis	16:00 - 16:30 Maria Claudia da Silva Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis
17:00 - 18:00	Twilight conference Chair: Roque Pacheco	Twilight conference Chair: Dario Zamboni	Twilight conference Chair: Camila Indiani
17:00 - 18:00	Edgar de Carvalho Use of topical imunomodulators in the therapy of cutaneous Leishmaniasis	Fernando Cunha Do neutrophil extracellular traps (NETs) play a relevant role in the pathology of inflammatory diseases?	Walderez Dutra Using immunoregulatory networks to instruct therapeutic interventions in human parasitic diseases
18:00 - 18:30	Coffee Break	Coffee Break	Coffee Break

		Açores Room
18:30 - 19:30	KEYNOTE CONFERENCE CHAIR: RODRIGO CORREA
	FIONA POWRIE GUT REACTIONS: IMMUNE PATHWAYS IN THE INTESTINE IN HEALTH AND DISEASE

		Cascaes Room
19:30 - 22:00	Poster Session with Happy Hour

	Pico Room	Ilha Room	São Miguel Room	Flores Room
7:30 - 8:30				BD Biosciences course in Immunotherapy Lucas Rizzo High dimension cell-Analysis in immunotherapy: Expanding cell boundaries by integrating sorting and transcriptome
8:30 - 9:00	Break	Break	Break
9:00 - 11:00	Joint Symposium with the Society for Leukocyte Biology (SLB) in Target leukocyte for immunotherapy Chair: Martin Bonamino	Symposium in Vaccines Chair: Helder Nakaya	Extra Section of Clinical Immunology (ESCI) Joint Symposium with the Brazilian Association of Allergy and Immunology (ASBAI) in Allergic diseases Chair: Edecio Cunha-Neto
9:00 - 9:30	Miriam Werneck In vitro differentiated memory cells as a tool for immunotherapy	Ricardo Palacios Dengue vaccine immune response: Between wishful thinking and good enough	João Negreiros Tebyriçá Allergy Immunotherapy: Immunological mechanisms and clinical indications
9:30 - 10:00	Marco Davila Mutation of the CD28 endodomain confers resistance of CAR-T cells to exhaustion	Olindo Martins Filho Impact of synthetic and biological immunotherapy on the duration of immunity induced by the 17DD yellow fever vaccine	Pedro Giavina Bianchi Immunomodulation of type 2 inflammation with monoclonal antibodies
10:00 - 10:30	Sven Brandau Tumor-associated neutrophils: Mediators of tumor progression and targets for combination immunotherapy	Esper Kallas Development of vaccines to prevent Zika	Momtchilo Russo Specific immunotherapy associated with TLR9 agonist for experimental asthma
10:30 - 11:00	Jose Conejo-Garcia Coordinated T and B cell responses spontaneously protect against ovarian cancer progression	Daniela Ferreira Experimental human pneumococcal challenge for vaccine development	Caroline Sokol Innate control of allergic immunity: New players, new pathways
11:00 - 11:30	Coffee Break	Coffee Break	Coffee Break
11:30 - 12:30	Morning conference Chair: João Trindade Marques	Morning conference Chair: Karina Bortoluci	Extra Section of Clinical Immunology (ESCI) Morning conference Chair: Lis Antonelli
11:30 - 12:30	Rosa Bacchetta Lentiviral-mediated gene transfer to convert T cells into Treg cells: New generation immune therapies	Ricardo Gazzinelli The circadian cycle and malaria: The sweet side of the story	Irini Sereti Idiopathic CD4 lymphopenia: A new kid on the autoimmunity block?
12:30 - 15:30	Lunch	Lunch	Lunch
12:30 - 14:00	SBI general assembly (13:30-15:00)	Satellite symposium	Satellite symposium
14:00 - 15:30	Break	Break	Break
15:30 - 17:00	Express presentation in Tumor and clinical immunology Chair: Rodrigo Ramos	Express presentation in Immuneregulation in diseases Chair: Larissa Cunha	Express presentation in Immunotherapy and vaccine Chair: Eduardo Lani Silveira
15:30 - 15:52	Rodrigo Ramos Unrevealing tumor-associated macrophages heterogeneity in breast cancer patients	Larissa Cunha The role of autophagy in the functional polarization of tumor-associated macrophages	Eduardo Lani Silveira Tryptophan metabolism drives the Dengue virus-mediated B cell differentiation into antibody-secreting cells
15:52 - 16:09	Murillo Duarte Silva The use of biologicals in top-down approach: a more promising strategy to induce remission and inflammation control in Crohn’s disease patients under anti-TNF therapy	Camila Figueiredo Pinzan Melatonin treatment restores the balance between activated and regulatory responses in intestinal immunity during experimental Toxoplasma Gondii infection	Alexandre de Magalhães Vieira Machado Assessment of the protective efficacy of a vaccine based on a recombinant influenza virus against S. Pneumoniae
16:09 - 16:26	Glauco Akelinghton Freire Vitiello Identification of MMTV-env sequences in Brazilian breast cancer patients and in silico predicted epitopes from MMTV Env protein as potential immunogenic targets	Cristhiane Favero de Aguiar Tissue-specific regulation of NKT cell metabolism drives their function and contributes to obesity	Isaú Henrique Noronha Intranasal vaccine against Trypanosoma cruzi mediates antibody protective responsi
16:26 - 16:43	Luciana Rodrigues Carvalho Barros Three-compartment mathematical model CAR-T cell immunotherapy	Renato da Silva Cardoso Relationship between cholinergic anti-inflammatory pathway and wound healing process: a perfect match?	Victória Alves Santos Lunardelli Immunization with different ZIKV envelope proteins induces long-term humoral and cellular immunity in mice
16:43 - 17:00	Nayara Gusmão Tessarollo Down-regulation of neoantigens promoted by treatment of B16F10 cells with P19ARF and IFN-	Wesley Nogueira Brandão NMDA ionotropic receptor signalling on the ontogeny of T-lymphocytes and its repercussion in the development of experimental autoimmune encephalomyelitis	João Pedro da Silva Nunes Assessment of the immunogenicity of the leptospiral Lipl32, ligani, and ligbrep recombinant proteins in the sheep model
17:00 - 17:30	Coffee Break	Coffee Break	Coffee Break

		Açores Room
17:30 - 18:30	CLOSING CONFERENCE CHAIR: Ricardo Gazzinelli
	JORGE KALIL FUTURE OF VACCINES: THE FIRST IMMUNOMODULATOR
18:30 - 19:00	Awards announcement and Closing remarks