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All SBI students and pos-doc are eligible for financial support See rUles here

SBI 2019 – Pre-congress course Immunobiology in the era of immunotherapy

September 28, 2019

Lecture series: concepts underpinning immune system dynamics

08:30 – Welcoming remarks
08:50 – 09:30 – Innate immunity and allergic immune response (Caroline Sokol – Harvard Medical School)
09:30 – 10:10 – Dynamics of immune system in the bone marrow (Karl Balabanian – Saint-Louis Research Institute)
10:10 – 10:50 – B cell dynamics in germinal centers (Lisa Westerberg- Karolinska Institutet)
10:50 – 11:10 – Coffee brake
11:10 – 11:50 – Molecular control of immune cell motility (Loïc Dupré – Center for Pathophysiology of Toulouse Purpan )
11:50 – 12:30 – Oral Tolerance (Ana Maria Caetano de Faria – UFMG)

General discussion
12:40 – 14:30 – Lunch brake

Immunotherapy Tools (14:30 – 16:30)

Each student will attend 1 seminar in each of the following sessions:

First session (14:30 – 15:30)
Groups A + B – Keys to design an immunotherapy project (Eliane Piaggio – Institute Curie)
Groups C + D – Developing relevant preclinical models to test immunotherapeutic reagents (Emmanuel Donnadieu – Institute Cochin)

Second session (15:30 – 16:30)
Groups A – Biomaterials in bone-marrow modeling (Adrienne Anginot -Saint-Louis Research Institute)
Groups B – Building CAR-T cells (Martin Bonamino – INCA)
Groups C – Optogenetics and in vivo imaging on leukocyte migration (Minsoo Kim – University of Rochester)
Groups D – Intravital microscopy (Gustavo Menezes – UFMG)

Immunotherapy Creative Tank

16:30 – 18:30
Students will be divided in 8 groups. Creativity will be stimulated and guided (by lecturers and instructors) towards the elaboration of a virtual scientific project aiming at developing an innovative therapeutical approach. They will use information collected through the morning lectures and the afternoon sessions on methods.

Proposed projects:
Group 1 – “Biomaterials to model and manipulate BM ecosystem in the context of leukemia” (Adrienne Anginot/ Karl Balabanian/ Eliane Piaggio)
Group 2 – “Tailoring therapy with optogenetics” (Minsoo Kim/ Arnon Jurberg)
Group 3 – “Elaboration of a drug screen to stimulate therapeutic T cell motility towards tumors” (Yolla German/ Jens Stein)
Group 4 – “How to stop malignant B cell responses: new approaches to treat B cell lymphoma” (Lisa Westerberg/ Amanda Torrentes)
Group 5 – “Therapeutic T lymphocytes with enhanced cytotoxic activity: design and monitoring” (Loic Dupré/ Maria Bellio)
Group 6 – “Targeting Neuro-Immune Interactions to Treat Allergic Diseases” (Caroline Sokol/ Vinicius Cotta-de- Almeida)
Group 7 – “Next-generation CAR-T cells” (Emmanuel Donnadieu/ Martin Bonamino)
Group 8 – “Oral tolerance: a physiological mechanism with therapeutical applications” (Ana Caetano/ Adriana Bonomo)

Requested output (common to each group):
– Ten-minute presentation of the designed immuno-therapeutical approach (Sunday morning activity)

September 29, 2019

Harnessing immune system rules to design immunotherapies

08:30 – 09:10 – Chemokine-dependent and -independent motility in CD8+ T cell subsets (Jens Stein – University of Fribourg)
09:10 – 11:00 – Presentation of students’ projects
11:00 – 11:20 – Coffee brake
11:20 – 13:00 – Overcoming barriers to T cell motility in tumors (Emmanuel Donnadieu – Institute Cochin)

Institutional Support

 

Venue and Contacts

 

Est. Ver. Onildo Lemos, 2505 - Praia do Santinho - Florianópolis, SC

Organized By
Congress Secretariat

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Sociedade Brasileira de Imunologia
Av. Prof. Lineu Prestes, 2415
São Paulo - SP - CEP 05508-000
sbi@sbi.org.br
Phone: +55 11 3034-2632