TUMOR IMMUNOLOGY (TU)

TU1 – DESIGNING CARS FOR PERSONALIZED IMMUNOTHERAPY BY RAPID ASSEMBLY FROM PRINCIPAL COMPONENTS USING “EZ-CAR” PLATFORM
ANA BEATRIZ CORREA KORNGOLD; BRIAN A RABINOVICH; HELEN H HULS; LAURENCE LJ COOPER

TU2 – TRANSFERENCE OF TUMOR-SPECIFIC MHC/PEPTIDE COMPLEXES TO DENDRITIC CELLS VIA EXOSSOMES
CAROLINA MENDONÇA GORGULHO; GRAZIELA GORETE ROMAGNOLI; REBECA SAYURI SALVUCCI HAMA; DANIEL JESUINO BASSETO; JOSÉ ROBERTO LUZZI; AURO DEL GIGLIO; RAMON KANENO

TU3 – FLAVONOID RUTIN AND QUERCETIN ARE CAPABLE OF MODULATING THE IMMUNE RESPONSE OF MICROGLIA / MACROPHAGES AND INHIBIT THE MIGRATION OF GLIOMA CELLS.
ALESSANDRA BISPO DA SILVA; KARINA COSTA SILVA; JOANA LUZ OLIVEIRA; PAULO LUCAS CERQUEIRA COELHO; RAMON DOS SANTOS EL-BACHÁ; MARIA DE FATIMA DIAS COSTA; VICTOR DIOGENES AMARAL DA SILVA; SILVIA LIMA COSTA

TU4 – MODULATION OF LIPID DROPLETS BIOGENESIS BY TOCOPHEROLS IN BREAST CANCER CELLS
BEATRIZ CHRISTINA LUZETE; LARISSA FERNANDA MELO VASCONCELOS; AZADEH MEHDAD; KELLY GRACE MAGALHÃES; MARINA KIYOMI ITO; NATHALIA MARCOLINI PELUCIO PIZATO

TU5 – EFFECT OF INSULARIN (GST-INS) ON INHIBITION ADHESION OF ENDOTHELIAL AND MELANOMA CELL TO PLATELETS
RAFAELA SILVA MENDONÇA; LILIAN GOMES DE OLIVEIRA; PATRICIA BIANCA CLISSA; IARA CAMARGO LIMA; GERALDO SANTANA MAGALHÃES; DURVANEI AUGUSTO MARIA; MAISA SPLENDORE DELLA CASA

TU6 – GASTRIN-RELEASING PEPTIDE INDUCES MIGRATION BUT NOT PROLIFERATION OF A NON-SMALL CELL LUNG CANCER CELL LINE IN VITRO
NATÁLIA JAEGER; RAFAEL SANGUINETTI CZEPIELEWSKI; MAIRA BAGATINI; BÁRBARA NERY PORTO; CRISTINA BONORINO

TU7 – EVALUATION OF THE ASSOCIATION OF ALUMINUM HYDROXIDE WITH PLGA NANOPARTICLE IN THE RESOLUTION OF THE EXPERIMENTAL TUMOR
GABRIELA CRISTINA FERREIRA BORGES; LAYANNY SILVEIRA PRAXEDES; BRUNO FERREIRA MARTINS LIBERATO; JACKELINE ALVES FÉLIX DE FREITAS; GUYLHERME – SARAIVA; DAVID CARVALHO RESENDE; FLÁVIA APARECIDA DE OLIVEIRA; ANDRÉ CORREA AMARAL; LUCIMEIRE ANTONELLI DA SILVEIRA

TU8 – BLOCKADE OF A2A RECEPTOR PROMOTES REDUCTION OF THE METASTATIC MAMMARY TUMOR
GRETEL RODRÍGUEZ RODRÍGUEZ; VERÔNICA M SALTARRELLI; VANESSA PEREIRA CARREGARO; LUCIANA BENEVIDES BENEVIDES; JOÃO SANTANA SILVA

TU9 – IMMUNOSTIMULATORY CANCER THERAPY USING DENDRITIC CELL-TUMOR CELL HYBRIDS
MARIANA PEREIRA PINHO; PATRICIA CRUZ BERGAMI-SANTOS; JOSÉ ALEXANDRE MARZAGÃO BARBUTO

TU10 – CHARACTERIZATION OF KERATINOCYTES APOPTOSIS FOLLOWING UVB OR CHEMOTHERAPY
CAROLINA LOPES QUINA; NATHALIA CRUZ DE VICTO; JOÃO GUSTAVO PESSINI AMARANTE-MENDES; JACQUELINE DE FÁTIMA JACYSYN

TU11 – COMBINED P19ARF AND INTERFERON-BETA GENE TRANSFER: EVIDENCE FOR INDUCTION OF IMMUNOGENIC CELL DEATH
RUAN FELIPE VIEIRA MEDRANO; JOÃO PAULO PORTELA CATANI; ALINE HUNGER RIBEIRO; BRYAN ERIC STRAUSS

TU12 – INTERACTION BETWEEN SENSITIZE HUMAN MAST AND DENDRITIC CELLS INDUCE REGULATORY T LYMPHOCYTE
CECILIA PESSOA RODRIGUES; JOSÉ ALEXANDRE MARZAGÃO BARBUTO

TU13 – DEVELOPMENT OF A NEW STRATEGY FOR CANCER MONOCLONAL ANTIBODY THERAPY USING A LIGAND FOR NATURAL KILLER (NK) CELLS RECEPTOR
VINICIUS DA CUNHA LISBOA; ENEIDA ALMEIDA SANTOS; MARIA DA GLÓRIA MARTINS TEIXEIRA; CARLOS OTÁVIO ALVES VIANNA; ALINE DE ALMEIDA OLIVEIRA

TU14 – CELL SIGNALING AND ACTIVATION MARKERS IN CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTORS (CARS)
PAULA CRISTINA DIAS DA SILVA; LEONARDO CHICAYBAM PEIXOTO; MAYRA CARNEIRO; MARTIN BONAMINO

TU15 – EVALUATION OF IMMUNOHISTOCHEMISTRY MARKERS ASSOCIATED WITH TUMOR METASTATIC PROGRESSION IN OBESE MICE
ANA CRISTINA MOURA GUALBERTO; DIEGO DE ASSIS GONÇALVES; GABRIELA COELI MENEZES EVANGELISTA; FELIPE HENRIQUE DA CUNHA XAVIER; MARIA JULIA DE ANDRADE E AZEVEDO SODRÉ MEEWES; SARA MALAGUTI ANDRADE SOARES; POLLYANNA AMARAL SALVADOR; JACY GAMEIRO

TU16 – ABSENCE OF NKCD56BRIGHT CELLS AND DYSFUNCTIONAL NKCD56DIM CELLS IN SÉZARY SYNDROME.
KELLY CRISTINA GOMES MANFRERE; MARINA PASSOS TORREALBA; JOSENILSON FEITOSA DE LIMA; GABRIEL COSTA DE CARVALHO; ALBERTO JOSÉ DA SILVA DUARTE; JOSE ANTONIO SANCHES; MARIA NOTOMI SATO

TU17 – UPREGULATION OF PD-1 AND CD38 EXPRESSION IN DISTINCT MATURATION PHASES OF CD8+ T CELLS IN PERIPHERAL BLOOD OF PATIENTS WITH SEZARY SYNDROME
MARINA PASSOS TORREALBA; KELLY CRISTINA GOMES MANFRERE; JOSENILSON FEITOSA DE LIMA; GABRIEL COSTA DE CARVALHO; ALBERTO JOSÉ DA SILVA DUARTE; MARIA NOTOMI SATO; JOSE ANTONIO SANCHES

TU18 – TUMOR MICROENVIRONMENT ACTS DIRECT AND SYSTEMICALLY SKEWING BLOOD MONOCYTES INTO SUPPRESSIVE CD163HIGHIL-10HIGH CELLS THAT MAY IMPACT IN CANCER PATIENTS’ SURVIVAL
RODRIGO NALIO RAMOS; CÉLINE RODRIGUEZ; SOPHIE LÉON; ISABELLE TREILLEUX; CAROLA RIES; EMILIE LAVERGNE; SYLVIE CHABAUD; CHRISTOPHE CAUX; JOSÉ ALEXANDRE MARZAGÃO BARBUTO; NATHALIE BENDRISS-VERMARE; CHRISTINE MÉNÉTRIER-CAUX

TU19 – ANTITUMORAL EFFECTS OF A NEW PPARG AGONIST IN BREAST CANCER CELL LINE
ERIKA PEREIRA SAMPAIO; LUIZ ANTÔNIO SOARES ROMEIRO; JOSÉ RAIMUNDO CORREA; KELLY GRACE MAGALHÃES

TU20 – PAFR-DEPENDENT MECHANISMS SHIFTS TUMOR MACROPHAGES TOWARDS REGULATORY PHENOTYPE AND REDUCES MELANOMA GROWTH IN MICE
ILDEFONSO ALVES DA SILVA-JR; ANA PAULA LEPIQUE; SONIA JANCAR

TU21 – ESSENTIAL OIL OF OCIMUM GRATISSIMUM L. REDUCES TGF-BETA 1 PRODUCTION IN LUNG CANCER CELL LINE
ERICK ESTEVES OLIVEIRA; CAIO CESAR SOUSA ALVES; SANDRA BERTELLI RIBEIRO DE CASTRO; DANIEL SALES PIMENTA; LUCIANA MOREIRA CHEDIER; ANA PAULA FERREIRA

TU22 – CONSTRUCTION AND VALIDATION OF AN ACTIVATING AND INHIBITORY CHIMERIC ANTIGEN RECEPTOR (CAR) SYSTEM AS A STRATEGY TO KILL SPECIFICALLY TUMOR CELLS
LEONARDO CHICAYBAM PEIXOTO; MARTIN BONAMINO

TU23 – MAB ANTI-FGF2 3F12E7 INHIBITS FGF-2 BINDING TO HUMAN ENDOTHELIAL CELLS
CAMILA BRAGGION; JÉSSICA DE SOUZA SANCHES; JANE ZVEITER DE MORAES

TU24 – BREAST CANCER CELLS LIPID DROPLETS ARE MODULATED BY ADJACENT ADIPOCYTES AND ARE RELATED WITH CANCER CELL PROLIFERATION CAPABILITY
LIVIA PIMENTEL DE SANT’ANA DOURADO; JOSÉ RAIMUNDO CORREA; KELLY GRACE MAGALHÃES

TU25 – EVALUATION OF CYTOTOXICITY AND TNF-Α RELEASE BY PALLADIUM (II) COMPLEXES
FRANCINE ALESSANDRA MANENTE; FILLIPE VIEIRA ROCHA; CAIO CESAR FURUNO; ADELINO VIEIRA DE GODOY NETTO; LUCAS SOUZA FERREIRA; AMANDA COSTA GONÇALVES; JULIANA APARECIDA JELLMAYER; MARISA CAMPOS POLESI PLACERES; IRACILDA ZEPPONE CARLOS

TU26 – LIPID BODIES IN ESOPHAGEAL CANCER: THE ROLE OF TLR4 ACTIVATION
NINA CARROSSINI BASTOS; NATHALIA OLIVEIRA MEIRELES; TANIA MOITA BLANCO; IVANIR MARTINS DE OLIVEIRA; LUCIANA WERNERSBACH PINTO; GILBERTO REINALDO MANSUR; PATRICIA TORRES BOZZA; JOAO P.B. VIOLA; LUIS FELIPE RIBEIRO PINTO

TU27 – HIGH LEVELS OF CD56+CD8+CD3- SUBSET IN PATIENT WITH TRIPLE-NEGATIVE BREAST CANCER: CASE REPORT
CLAUDEIR DIAS DA SILVA JUNIOR; JOSE FERNANDO DO PRADO MOURA; ROSANNE VENTURA DE CARVALHO; ALEXANDRA KARLA SANTOS BARRETO; LEURIDAN CAVALCANTE TORRES

TU28 – IN VIVO THERAPY WITH CARBON NANOPARTICLES MODIFIES THE PROFILE OF REGULATORY T CELLS IN TUMOR MICROENVIRONMENT
INGRID ROSA; ROSEMEIRE FLORENÇA DE PAULA; ADRIEL SANTOS MORAES; INGRID FELIX MAIA GAFANHÃO; ALEXIA OLIVEIRA; VINICIUS BOLDRINI; FERNANDO PRADELLA; ALFREDO PETERLEVITZ; SILVIA IRAZUSTA; HELDER CERAGIOLI; ALESSANDRO S. FARIAS; LEONILDA MARIA BARBOSA DOS SANTOS; ELAINE CONCEIÇÃO DE OLIVEIRA; VITOR BARANAUSKAS

TU29 – THERAPEUTIC EVALUATION OF EHRLICH TUMOR BEARING MICE TREATED WITH ETHANOL EXTRACTS OF COPAIFERA MULTIJUGA HAYNE
LUCINEIA REUSE ALBIERO; EDUARDO FIGUEREDO NERY; TAIANY OLIVEIRA KELLY; JENIFFER CHARLENE DALAZEN; DEBORA LINSBINSKI PEREIRA; LINDSEY CASTOLDI

TU30 – THERAPEUTIC EVALUATION OF MICE BEARING EHRLICH’S CARCINOMA AND TREATED WITH ETHANOL EXTRACTS OF AVELOZ (EUPHORBIA TIRUCALLI L)
EDUARDO FIGUEREDO NERY; JENIFFER CHARLENE DALAZEN; LUCINEIA REUSE ALBIERO; TAIANY OLIVEIRA KELLY; LINDSEY CASTOLDI

TU31 – EVALUATION OF THE ROLE OF FLAGELLIN IN SALMONELLA MEDIATED ANTI-TUMOUR RESPONSE
MARÍA MORENO; AMY MONACO; LUCIA YIM; JOSE ALEJANDRO CHABALGOITY

TU32 – MIGRATION KINETICS OF IMMUNE CELLS IN MURINE MELANOMA MODEL
JOSÉ RENILDO CARVALHO; EDILAINE SUDRE MARCELINO NASCIMENTO; FABIANA TOSHIE CAMARGO KONNO; ELIZABETH CRISTINA PEREZ HURTADO

TU33 – B-1 CELLS, NEW COMPONENT OF THE TUMOR MICROENVIRONMENT IN 4T1 BREAST CANCER MODEL
EDILAINE SUDRE MARCELINO NASCIMENTO; JOSÉ RENILDO CARVALHO; FABIANA TOSHIE CAMARGO KONNO; ELIZABETH CRISTINA PEREZ HURTADO

TU34 – MIRNAS FOR OPTIMIZE THE RESPONSE OF T LYMPHOCYTE MODIFIED BY CHIMERIC ANTIGEN RECEPTOR (CAR)
MAYRA CARNEIRO

TU35 – EFFECT OF MINIMUM-EFFECTIVE AND NON-TOXIC CONCENTRATIONS OF 5 FLUOROURACIL ON THE CHEMOIMMUNOMODULATION OF HUMAN DENDRITIC CELLS
SOPHIA MIQUELLE CERON GIMENEZ RIBEIRO SARTORI; GRAZIELA GORETE ROMAGNOLI; CAROLINA MENDONÇA GORGULHO; RAMON KANENO

TU36 – THE ROLE OF INFLAMMATORY MICROENVIRONMENT IN MODULATION OF TUMORAL PROPERTIES IN PROSTATE CANCER CELLS IN VITRO
RAFAELA SALGADO FONTENELE; KELLY GRACE MAGALHÃES; JOSÉ RAIMUNDO CORREA

TU37 – ALLOGENEIC EXOSOMES FROM DENDRITIC CELLS INDUCE REGULATORY PROFILE ON T LYMPHOCYTES
GRAZIELA GORETE ROMAGNOLI; REBECA SAYURI SALVUCCI HAMA; CAROLINA MENDONÇA GORGULHO; DANIEL JESUINO BASSETO; JOSÉ ROBERTO LUZZI; AURO DEL GIGLIO; RAMON KANENO

TU38 – NLRP3 INFLAMMASOME ACTIVATION HAS AN ANTITUMORIGENIC EFFECT ON BREAST CANCER CELLS IN VITRO
NATHALIA MORAES DE VASCONCELOS; JOSÉ RAIMUNDO CORREA; KELLY GRACE MAGALHÃES

TU39 – ALLOGENEIC EXOSOMES INDUCE SUPPRESSIVE EFFECT IN DENDRITIC CELLS ACTIVATION AND IN THEIR NANOVESICLES
REBECA SAYURI SALVUCCI HAMA; JOYCE ZALOTTI BRANDT; WELLERSON RODRIGO SCARANO; JOSÉ ROBERTO LUZZI; RAMON KANENO; GRAZIELA GORETE ROMAGNOLI

TU40 – GENOMIC EDITING OF PD-1 LOCUS IN T LYMPHOCYTES.
BÁRBARA COSTA PEIXOTO; LEONARDO CHICAYBAM PEIXOTO; MARTIN BONAMINO

TU41 – EOMESODERMIN REGULATES THE EARLY ACTIVATION OF ALLOREACTIVE CD4 T CELLS AND IS CRITICAL FOR BOTH GVH AND GVL RESPONSES
BARBARA DU DU ROCHER; ODETTE SMITH; ANDREW M. INTLEKOFER; JARROD A. DUDAKOV; EMILY LEVY; FABIANA KREINERS; STEVEN REINER; ELIANA ABDELHAY; MARCEL VAN DEN BRINK; ALAN M. HANASH

TU42 – NEUTROPHILS COUNT AND CELL MATURITY AS PROGNOSTIC INDICATORS IN BREAST CANCER PATIENTS.
MARIA ANGÉLICA OLIVEIRA MENDONÇA

TU43 – UPTAKE OF CARBON NANOTUBES BY LEWIS LUNG CARCINOMA CELLS MODIFIED IN VIVO THE TUMOR GROWING – PRELIMINARY DATE
ALEXIA OLIVEIRA; INGRID FELIX MAIA GAFANHÃO; INGRID ROSA; ADRIEL SANTOS MORAES; ROSEMEIRE FLORENÇA DE PAULA; VINICIUS BOLDRINI; FERNANDO PRADELLA; SILVIA IRAZUSTA; HELDER CERAGIOLI; ALFREDO PETERLEVITZ; ALESSANDRO S. FARIAS; LEONILDA MARIA BARBOSA DOS SANTOS; VITOR BARANAUSKAS; ELAINE CONCEIÇÃO DE OLIVEIRA

TU44 – LYMPH NODE CELL POPULATION EVALUATION IN OBESES MICE BALB/C INDUCED WITH BREAST TUMOR
GABRIELA COELI MENEZES EVANGELISTA; POLLYANNA AMARAL SALVADOR; ANA CRISTINA MOURA GUALBERTO; SARA MALAGUTI ANDRADE SOARES; FELIPE HENRIQUE DA CUNHA XAVIER; MARIA JULIA DE ANDRADE E AZEVEDO SODRÉ MEEWES; DIEGO DE ASSIS GONÇALVES; JACY GAMEIRO

TU45 – HIGH SERUM LEVELS OF PROINFLAMMATORY CYTOKINES IN PATIENTS WITH ORAL SQUAMOUS CELL CARCINOMA
CAMILA DA SILVA SOUZA; RAFAEL DA FONSECA CARVALHO; ROSALINA GUEDES DOS SANTOS; ANDRÉ LEONARDO DE CASTRO COSTA; IVAN MARCELO GONÇALVES AGRA; LEONARDO DE SOUZA KRUSCHEWSKY; LUCAS GOMES SILVA; JEAN NUNES DOS SANTOS; SONGELÍ MENEZES FREIRE; LUCAS P. CARVALHO; ALEX LEITE TORRES; ROBERTO MEYER; DEISE SOUZA VILAS-BÔAS

TU46 – HIGH-FAT DIET ALTERS THE BALANCE OF PRO INFLAMMATORY CYTOKINES IN BALB/C MICE WITH MAMMARY CARCINOMA
POLLYANNA AMARAL SALVADOR; GABRIELA COELI MENEZES EVANGELISTA; ANA CRISTINA MOURA GUALBERTO; MARIA JULIA DE ANDRADE E AZEVEDO SODRÉ MEEWES; FELIPE HENRIQUE DA CUNHA XAVIER; ADRIANA BONOMO; JACY GAMEIRO

TU47 – CYTOKINE PROFILES AND SOLUBLE HLA-G LEVELS IN PEDIATRIC T- CELL ACUTE LYMPHOBLASTIC LEUKEMIA
RENATA DOS SANTOS ALMEIDA; ALESSANDRA MARIA DE LUNA RAMOS; ESTER AUGUSTA VINHAS MARQUES; FRANCISCO PEDROSA; EDUARDO ANTÔNIO DONADI; NORMA LUCENA-SILVA

TU48 – IMMUNIZATION WITH MAB BEVACIZUMAB ANTI-ID 10.D7 CAUSES ANGIOGENIC ALTERATIONS
JÉSSICA DE SOUZA SANCHES; RODRIGO BARBOSA DE AGUIAR; JANE ZVEITER DE MORAES

TU49 – CONSTRUCTION AND CHARACTERIZATION OF ANTI-FGF2 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) FROM 3F12E7 HYBRIDOMA CELLS
TÁBATA DE ALMEIDA DA SILVA; MARCELO A MORI; JANE ZVEITER DE MORAES

TU50 – CD137 AND CD137L IN CHRONIC MYELOID LEUKEMIA
FERNANDA CAROLINE COIRADA OLIVEIRA; PATRICIA COUCEIRO; DÉBORA QUEIRÓS; DIOGO GOMES-SILVA; JANI ALMEIDA; ANDREIA DINIZ; LÚCIA MATOS; MÓNICA SERRA; DANIELA SANTO; PRISCILA MAZINI; JEANE ELIETE LAGUILA VISENTAINER; VERA ALVES; LENKA RŮŽIČKOVÁ; PAULO FREITAS-TAVARES; MANUEL SANTOS-ROSA; PAULO RODRIGUES-SANTOS