Day 1 – Oct 18 (Saturday)
15:00-18:00 Registration
18:00-18:30 Opening ceremony
18:30-19:30 Opening conference
Chair: Jorge Kalil
Dan Littman
Microbiota influence on inflammatory lymphocytes and autoimmune disease
19:30-21:00 Cocktail
Day 2 – Oct 19 (Sunday)
09:00-11:00 Symposium in Signaling
and gene regulation in immune cells
Chair: Eddy F.Y. Liew
Symposium in Mucosal immunology
Chair: Claudia Brodskyn
Extra Section of Clinical Immunology Symposium in Viral immunity
Chair: Dumith Chequer Bou-Habib
09:00-09:30 Geraldo Passos
Aire and microRNAs in the root of central tolerance
Daniel Mucida
Gut immune surveillance by intraepithelial lymphocytes
Daniel Mansur
Implications of a highly conserved Dengue E protein peptide for viral viability and vaccine design
09:30-10:00 Gustavo Amarante Mendes
Galectin-1 as a novel effector molecule of CTLs
Momtchilo Russo
Multiple pathways in the control of allergic inflammation
Luisa Villa
Immune responses to HPV VLPs: Durability and real-world impact of HPV vaccination
10:00-10:30 Fernando Macian
Coordinated regulation of T cell activation by distinct forms of autophagy
Ana Maria Caetano
Anti-inflammatory lipids and their effects in the gut
Victor Appay
CD8+ T cell efficacy against HIV: Priming the right cells
10:30-11:00 Francesca Granucci
Mechanisms and consequences of NFAT signaling pathway activation in innate immune cells
Alexander Chervonsky
Maintenance of host-microbiota symbiosis during sickness
Douglas Nixon
HIV pathogenesis and vaccine design
11:00-11:30 Coffee break
11:30-12:30 Morning conference
Chair: Maria Bellio
Morning conference
Chair: Walderez Dutra
Extra Section of Clinical Immunology
Morning conference
Chair: Helder Nakaya
Oreste Acuto
T cell antigen receptor signaling and autoimmunity
Marco Colonna
Innate lymphoid cells in mucosal immunity
Bali Pulendran
Systems vaccinology: Enabling rational vaccine design with systems based approaches
12:30-15:30 Lunch
12:30-15:00 BD Biosciences satellite symposium
*Lunch box will be provided
Optimize your Multicolor Panel with BD
Bring your panel, doubts and challenges
15:00-15:30 Break
15:30-16:30 Twilight conference
Chair: Fernando Cunha
Twilight conference
Chair: Camila Indiani de Oliveira
Jorge Kalil
The effort to obtain vaccines that Brazil needs
Federica Sallusto
Class and specificity of the human T cell response to pathogens and vaccines
16:30-18:00 Express presentation in Molecular immunology
Chair: Aristóbolo Mendes da Silva
Express presentation in Innate immunity
Chair: Karina Bortoluci
Express presentation in
Immunity to infection and host defense
Chair: Thiago Moreno Souza
16:30-16:52 Aristóbolo Mendes da Silva
Negative regulation of Toll-like receptor (TLR)-inflammatory signaling
Karina Bortoluci
Role of lysosomal pathway induced by flagellin in cell death and immunity
Thiago Moreno Souza
Innate immune response during HIV-1 co-infection with other viruses
16:52 – 17:09 Milene Mesquita
HIV-1 and its GP120 inhibits the influenza A(H1N1)PDM09 life cycle in an IFITM3-dependent fashion
Suelen Diniz
The CD14+CD16+ monocyte subset displays increased mitochondrial activity during Plasmodium vivax infection
Henrique Borges da Silva
In vivo approaches reveal a key role for DCs for CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria
17:09 – 17:26 Marcelle de Carvalho Ribeiro
Differential modulation of mTOR complexes in monocytes adhesion induced by LPS and phorbol ester
Natalia Ketelut-Carneiro
Inflammasome-derived IL-18 production induces Th1-mediated resistance to Paracoccidioides brasiliensis
Rafael Moysés Salgado
Trypanosoma cruzi exit from the blood circulation: Involvement of antibodies
17:26 – 17:43 Simone Gonçalves Fonseca
PD-1 inhibits TCR signaling by recruitment of inhibitory molecules to the immunological synapse
Brener Cunha Carvalho
Ras-related protein RAP2A as a new regulatory checkpoint molecule on NF-KappaB activation in Toll-like receptor (TLR)-signaling pathway
Jonatan Ersching
Dendritic cell exposure to Trypanosoma cruzi leads to the suppression of CD8+ T cell response
17:43 – 18:00 Diane Sthefany Lima de Oliveira
Variable-region identical antibodies of different IgG isotypes show different binding patterns to Cryptococcus neoformans
Olivier Lamiable
Diedel, an immunomodulator molecule, involved in homeostasis during Sindbis infection in Drosophila
Fanny Tzelepis
Annexin 1 is critical in immunity to Mycobacterium tuberculosis infection by mediating DC efferocytosis and antigen cross-presentation
18:00-18:30 Coffee break
18:30-19:30 SBI lifetime achievements award in immunology
Chair: Manoel Barral Netto
Marcello Barcinski
Some considerations on doing science in a developing country
Hosted by George dos Reis
19:30-21:30 Poster session
Day 3 – Oct 20 (Monday)
09:00-11:00 Symposium in
Chair: Joseli Lannes-Vieira
Symposium in
Cell metabolism in the immune response
Chair: Patricia Bozza
Extra Section of Clinical Immunology
Symposium in Vaccines
Chair: Ricardo Gazzinelli
09:00-09:30 Pedro Campos Lima
Immunomodulation by short and long chain n-alkanols
Niels Olsen
Role of MyD88 in obesity-induced inflammation
Helder Nakaya
Systems analysis of immunity to influenza vaccine in the young and the elderly
09:30-10:00 Adriana Gruppi
Plasma cells secrete more than antibodies
Carrie Lucas
Lymphoproliferation and prominent CD8 T cell senescence in primary human immunodeficiencies caused by gene mutations that activate PI3K signaling
Luís Carlos de Souza Ferreira
New insights into the quest of an effective anti-dengue vaccine
10:00-10:30 André Vale
Role of evolutionary conserved CDR-H3 sequences in the regulation of natural antibody immunity and B cell repertoires
Fernanda de Felice
Inflammation and defective brain insulin signaling in Alzheimer’s disease
Mauricio Rodrigues
Long-lived effector memory T cells and vaccines
10:30-11:00 Giuseppina Caligiuri
Immunoregulatory functions of CD31
Laszlo Nagy
The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages
Luiza Guilherme
Vaccine against S. pyogenes as a tool of prevention of Rheumatic Fever and autoimmune heart-lesions
11:00-11:30 Coffee break
11:30-12:30 Morning conference
Chair: Gustavo Amarante Mendes
Morning conference
Chair: Leonardo Teixeira
Extra Section of Clinical Immunology
Morning conference
Chair: Hugo Castro Faria Neto
Gabriel Rabinovich
Integrating immunoregulatory and vascular signaling programs through lectin-glycan interactions: A sweet liaison
Mark Ansel
MicroRNA regulation of the immune system
Miguel Soares
Gut microbiota elicits a protective immune response against malaria transmission
12:30-15:30 Lunch
12:30-15:00 SBI general assembly
BD Biosciences satellite symposium
*Lunch box will be provided
BD Horizon Tour: new insights for multicolor panel design
Robert Balderas
Alan Stall
Maria James
15:00-15:30 Break
15:30-16:30 Twilight conference
Chair: Edecio Cunha-Neto
Twilight conference
Chair: Lucas Carvalho
Ashley Haase
Fc Receptors in female reproductive tract epithelium: Roles in Delta-nef vaccine protection
Eddy F.Y. Liew
IL-33 in infection and inflammation
16:30-18:00 Express presentation in
Inflammation and
Chair: Jose Alves Filho
Express presentation in
Cellular and mucosal immunology
Chair: Bernardo Reis
Express presentation in
Immunotherapy and vaccine
Chair: Valéria Borges
16:30-16:52 Jose Alves Filho
Signaling and function of adenosine in sepsis-induced immunosuppression
Bernardo Reis
Transcription factor T-bet regulates intra-epithelial lymphocyte functional maturation
Valéria Borges
Arginase pathway contributes to tegumentary Leishmaniasis
16:52 – 17:09 Maria Fernanda de Souza Costa Silva
Protective gamma delta T lymphocytes accumulate in the lungs of severe septic mice and produce IL-17
Leandro Pires Araujo
The sympathetic nervous system modulates experimental autoimmune encephalomyelitis
Juliana de Souza Apostolico
Using a fusion monoclonal antibody to direct multiple HLA-DR binding CD4+ epitopes derived from HIV to dendritic cells in vivo
17:09 – 17:26 Luciana Pádua Tavares
Modulation of inflammatory response during Streptococcus pneumoniae infection prevents lung injury and improves the bacteria clearance in mice
Maria Emilia Zenteno
Effect of melatonin on CD4+ T lymphocyte-dependent immune response
Noemia Santana Lima
Expression o SIV envelope proteins by recombinant yellow fever vaccine induces humoral response in Balb/C mice
17:26 – 17:43 Raphael Gomes Ferreira
Indoleamine 2, 3-dioxygenase (IDO): A new trigger of sepsis-induced immunosuppression
Aline Ignacio
mTORC1 is essential to dendritic cells activation and to ulcerative colitis development
Thaize Quiroga Chometon Pedro
Assessment of in vitro Moreau BCG infection in human monocytes for the induction of mRNA related to apoptosis pathway in healthy volunteers
17:43 – 18:00 Clarissa Rodrigues Nascimento
Inflammatory edema elicited by Trypanosoma cruzi fuels heart tissue parasitism through the proteolytic activation of the kallikrein-kinin system
Fernanda Nuzzi Dias
Differentiation of Th17 cells in vivo by phagocytosis of infected apoptotic cells – role of PGE2
Rafael Barbosa Polidoro
Protective immunity and safety of a genetically modified influenza virus vaccine
18:00-18:30 Coffee break
18:30-19:30 Keynote conference
Chair: Sergio Costa Oliveira
Richard Flavell
Inflammasomes in dysbiosis and disease
19:30-21:30 Poster session
Day 4 – Oct 21 (Tuesday)
09:00-11:00 Symposium in
Tumor immunology and immunotherapy
Chair: Cristina Bonorino
Symposium in
Immunity to infection
Chair: Elvira Saraiva
Extra Section of Clinical Immunology
Symposium in
Immunoregulation in disease
Chair: Guy Zimmerman
09:00-09:30 Adriana Bonomo
T cells as messengers from the periphery to the hematopoietic bone marrow: Implications to the metastatic bone marrow niche
João Marques
Small non-coding RNAs in host-pathogen interactions
Ludmila Ferreira
Host microRNAs expression during T. cruzi infection and Chagas disease cardiomyopathy: A systems biology approach
09:30-10:00 João Santana
The pro-tumorigenic role of IL-17
André Bafica
A Mycobacterium tuberculosis ricin-like lectin regulates infection in macrophages
Pablo Baldi
Pulmonary innate immune response to Brucella infection
10:00-10:30 Sergei Grivennikov
Inflammatory cytokines as mediators of tumor elicited inflammation and tumor progression
Dario Zamboni
Inhibition of non-canonical activation of the inflammasome by intracellular pathogens
Hugo Castro Faria Neto
Neuro-inflammation and cognitive decline in infectious severe systemic inflammatory syndromes
10:30-11:00 Kevin Maloy
Innate immune circuits in protection and pathology in the intestine
Benedicte Manoury
Impact of proteolytic processing of endosomal Toll-like receptors in the innate and adaptive immune response
Antonino Nicoletti
Control of the Tfh-GC B cell axis by CD8+ Tregs limits atherosclerosis and tertiary lymphoid organ development
11:00-11:30 Coffee break
11:30-12:30 Morning conference
Chair: João Marques
Morning conference
Chair: Gustavo Menezes
Extra Section of Clinical Immunology
Morning conference
Chair: Jose Alves Filho
Jean-Luc Imler
Antiviral innate immunity in Drosophila
Gabriel Victora
Cellular and clonal dynamics in germinal centers
Roland Kolbeck
Cigarette smoke silences innate lymphoid cell function in the lung, facilitating an IL-33-dependent, exacerbated Th-1 response to infection
12:30-15:30 Lunch
12:30-15:00 Beckman Coulter satellite symposium
*Lunch box will be provided
SBI-BD Biosciences investigator award
Chair: Tiago Mineo
*Lunch box will be provided
New solutions for the acquisition and analysis in flow cytometry
Joyce Slusser
Margareth Fernandes
Finalist oral presentation
15:00-15:30 Break
15:30-16:30 Twilight conference
Chair: Alberto Nobrega
Twilight conference
Chair: Julio Scharfstein
SBI Thereza Kipnis award
Chair: Dario Zamboni
Hassan Jumaa
Role of self-recognition and BCR responsiveness in B cell development
Sebastian Amigorena
Antigen presentation in mouse and human dendritic cells
Carolina Lucas
Evaluation of autologous dendritic cells transfected with Lamp/Gag plasmid as an anti-HIV vaccine model
16:30-18:00 Express presentation in Tumor and clinical immunology
Chair: Martin Bonamino
Express presentation in Immuneregulation
Chair: Pritesh Lalwani
Pedro Elias Marques
Hepatic DNA deposition drives drug-induced liver injury and inflammation
16:30-16:52 Martin Bonamino
Chimeric Antigen Receptor (CAR) studies in tumor Immunotherapy
Pritesh Lalwani
Virus-induced release of neutrophil extracellular traps (NETS) links viruses with systemic lupus erythematosus (SLE)
Eugenio Hottz
Platelets mediate inflammatory amplification and immune modulation of monocytes in Dengue disease
16:52 – 17:09 Cecilia Pessoa Rodrigues
Interaction between sensitize human mast and dendritic cells induce regulatory T lymphocyte
Lucas Coelho Marliére Arruda
Autologous hematopoietic stem cell transplantation improves aberrant immunoregulatory network in multiple sclerosis patients
17:00 – 17:30
Thais Garcias Moreira
Conjugated linoleic acid-rich diet induces LAP+ Treg cells via PPARgamma and increase tumor infiltration on colon cancer model
17:09 – 17:26 Ildefonso Alves da Silva-Jr
PAFR-dependent mechanisms shifts macrophages towards regulatory phenotype and reduces melanoma growth in mice
Fátima Brant
Suppressor of cytokine signaling 2 (SOCS2) modulates experimental cerebral malaria pathogenesis
17:26 – 17:43 Barbara Du Rocher
Eomesodermin regulates the early activation of alloreactive CD4 T cells and is critical for both GVH and GVL responses
Rafael Pires de Oliveira
Type 1 diabetes exposes immunoregulatory defects in the gut of Nod mice
17:30 – 18:00
Eduardo Amaral
Pulmonary infection with hypervirulent mycobacteria reveals a crucial role for P2X7 receptor in aggressive forms of tuberculosis
17:43 – 18:00 Nina Carrossini Bastos
Lipid bodies in esophageal cancer: The role of TLR4 activation
João Paulo Martins do Carmo
Phenotype and cytokine profile of infiltrating cells in autoimmune hepatitis of Scurfy mice
18:00-18:30 Coffee break
18:30-19:30 Keynote conference
Chair: Mauricio Rodrigues
Michel Nussenzweig
Antibodies to HIV in prevention and therapy
19:30-21:30 Poster session
Day 5 - Oct 22 (Wednesday)
09:00-10:00 Morning conference
Chair: Patricia Bozza
Valérie Quesniaux
Membrane versus soluble TNFR1 and TNFR2 regulate host response to M. tuberculosis
10:00-11:00 Keynote conference
Chair: Rodrigo Correa de Oliveira
Sankar Ghosh
Regulation of NF-kB in immune and inflammatory responses
11:00-11:30 Coffee break
11:30-12:30 Closing conference
Chair: João Viola
Sergio Costa Oliveira
Internal affairs: Unraveling how stealthy intracellular bacteria are sensed by host innate immune receptors
12:30-13:00 Awards announcement and Closing remarks